diff --git a/Marlin/Configuration.h b/Marlin/Configuration.h
index 2639bcd97..d23b69c02 100644
--- a/Marlin/Configuration.h
+++ b/Marlin/Configuration.h
@@ -1604,9 +1604,12 @@
   // Move the nozzle to the initial position after cleaning
   #define NOZZLE_CLEAN_GOBACK
 
-  // Enable for a purge/clean station that's always at the gantry height (thus no Z move)
+  // For a purge/clean station that's always at the gantry height (thus no Z move)
   //#define NOZZLE_CLEAN_NO_Z
 
+  // For a purge/clean station mounted on the X axis
+  //#define NOZZLE_CLEAN_NO_Y
+
   // Explicit wipe G-code script applies to a G12 with no arguments.
   //#define WIPE_SEQUENCE_COMMANDS "G1 X-17 Y25 Z10 F4000\nG1 Z1\nM114\nG1 X-17 Y25\nG1 X-17 Y95\nG1 X-17 Y25\nG1 X-17 Y95\nG1 X-17 Y25\nG1 X-17 Y95\nG1 X-17 Y25\nG1 X-17 Y95\nG1 X-17 Y25\nG1 X-17 Y95\nG1 X-17 Y25\nG1 X-17 Y95\nG1 Z15\nM400\nG0 X-10.0 Y-9.0"
 
diff --git a/Marlin/src/libs/nozzle.cpp b/Marlin/src/libs/nozzle.cpp
index 21e6ffb7c..f93e55248 100644
--- a/Marlin/src/libs/nozzle.cpp
+++ b/Marlin/src/libs/nozzle.cpp
@@ -46,15 +46,24 @@ Nozzle nozzle;
 
     // Move to the starting point
     #if ENABLED(NOZZLE_CLEAN_NO_Z)
-      do_blocking_move_to_xy(start);
+      #if ENABLED(NOZZLE_CLEAN_NO_Y)
+        do_blocking_move_to_x(start.x);
+      #else
+        do_blocking_move_to_xy(start);
+      #endif
     #else
       do_blocking_move_to(start);
     #endif
 
     // Start the stroke pattern
     LOOP_L_N(i, strokes >> 1) {
-      do_blocking_move_to_xy(end);
-      do_blocking_move_to_xy(start);
+      #if ENABLED(NOZZLE_CLEAN_NO_Y)
+        do_blocking_move_to_x(end.x);
+        do_blocking_move_to_x(start.x);
+      #else
+        do_blocking_move_to_xy(end);
+        do_blocking_move_to_xy(start);
+      #endif
     }
 
     TERN_(NOZZLE_CLEAN_GOBACK, do_blocking_move_to(oldpos));